Projects

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USAID Emerging Pandemic Threats - PREDICT Project (2009-present)

Since 2009, HALI partners UC Davis and the Sokoine University of Agriculture have been working together to strengthen capacity inTanzania for surveillance and detection of viral threats that can move between animals and people. Through PREDICT, the HALI team has built a highly trained One Health workforce for surveillance or emerging viral threats and advanced the laboratory system for improved disease detection. Now in the second phase, PREDICT/Tanzania has expanded to include partners from the Ifakara Health Institute and launched concurrent surveillance of wildlife and people in at-risk areas for viral spillover and spread. In Tanzania the project has trained over 100 individuals in core One Health skills, sampled over 2,000 individuals (animals and people), and detected 63 viruses, including 50 viruses new to science.

 

Defense Threat Reduction Agency - One Health Approach to Surveillance of Rift Valley Fever virus and Brucella (R&B) (2015-2018)

The R&B project, initiated in 2015, is conducting surveillance and risk characterization for Rift Valley fever virus (RVFV) and Brucella exposure and isolates from animals, humans, and arthropod vectors in two regions of Tanzania. R&B is also contributing to Tanzania’s Global Health Security Agenda by strengthening local surveillance capacity for RVFV and Brucella detection, management, and control. To date the project has trained over 50 individuals in biosafety, safe sample collection, and disease detection, collected samples from over 3,700 domestic animals, 2,200 mosquito pools, and 4,000 febrile patients for disease testing.

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Defense Threat Reduction Agency - Evaluating Zoonotic Viral Sharing in South Tanzania (VISHA) (2015-2018)

VISHA, also initiated in 2015, is evaluating the risk of zoonotic viral disease transmission among bats, non-human primates (NHP), and people sharing a forest interface with high human-wildlife contact in Southern Tanzania. VISHA’s goals are to identify critical control points for disease transmission and to strengthen local  One Health surveillance capability to prevent regional or pandemic outbreaks of disease. To date, VISHA scientists from the Sokoine University of Agriculture, Ifakara Health Institute, and UC Davis have sampled more than 1,400 bats and 1,900 febrile patients, set tracking devices on bats to monitor their movement and potential disease transmission risk, and completed molecular testing for both priority zoonotic disease such as Ebola and Marburg along with new and emerging viral threats.

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Rx One Health (2017-)

The goal of Rx One Health is to provide a “prescription” or Rx for early career health professionals to prepare them for immediate engagement in global health careers that will demand effective problem solving skills, cross-disciplinary engagements, and solid foundations in field and laboratory activities.

Led by the UC Davis One Health Institute and Sokoine University of Agriculture, the Rx One Health curriculum has been built on the tremendous legacy of a course called Envirovet Summer Institute that was co-led by UC Davis and offered multiple times throughout the 1990s and 2000s, and which trained more than 400 veterinarians and veterinary students from around the world in ecosystem health (a precursor to One Health). Like Envirovet, Rx One Health is an immersion-style, hands-on, intensive training course delivered over a 4-week period, with all coursework occurring in Tanzania in 2018.

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Safari Club International Foundation - Ruaha Buffalo Project (2014-2017)

This project aimed to investigate an unexplained decline of African buffaloes in Ruaha National Park (RNP). Ruaha has traditionally been home to a large number of African buffalo herds that were considered the source population for the game reserves surrounding RNP, where both commercial and locally owned safari companies generate significant revenue through trophy hunting. HALI worked with RNP staff to investigate the decline of African buffaloes. Findings supported initial concerns about a population decline as significantly fewer buffaloes were counted in our 2013 aerial survey than in the last population survey conducted in 2004. We also documented the presence of bovine tuberculosis and brucellosis in Ruaha’s buffalo, two diseases which may impact population health through reduced fitness and reproduction. Finally, we showed that herd composition and cow:calf ratios varied substantially between 2011 and 2013, likely due to differences in precipitation.

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NIH - NIAID One Health Project (2009-2014)

Together with founding HALI partners UC Davis and the Sokoine University of Agriculture, the HALI team expanded its One Health network to include the University of Warwick, and the Tanzania National Medical Research Institute in order to more comprehensively address zoonotic disease transmission dynamics between the environment, animals, and people in Tanzania.  Our international One Health team worked together to improve tuberculosis surveillance, management and control in herds and households in pastoral areas of the greater Ruaha Ecosystem.

 

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USAID Feed the Future Innovation Lab Collaborative Research: Adapting Livestock Systems to Climate Change (2010-2014)

Building on work conducted through the Global Livestock CRSP (2006-2009), HALI, supported by an award through the USAID Feed the Future Innovation Lab “Adapting Livestock Systems to Climate Change” continued to partner with rural pastoralist communities to evaluate the impacts of education on livestock health, maternal and child nutrition, and livelihoods in Tanzania’s Ruaha ecosystem. To reach pastoralist households in remote areas, our team worked to develop a mobile phone-based disease reporting and education system and worked with district and regional health officials, village extension officers, and university partners to better understand disease threats and the potential for improving health service delivery. We also teamed up with the Friends of Ruaha Society, a local environmental education organization to bring climate change and health messages to primary schools.

 

USFWS Wildlife Without Borders Building Capacity and Awareness to Mitigate Conservation Threats from Zoonotic Diseases at the Wildlife-Livestock Interface in the Ruaha Ecosystem, Tanzania (2009-2010)

The overarching goal of this project was to develop the local capacity of Ruaha’s protected area managers and staff to diagnose and investigate disease threats to wildlife and raise awareness of protected area staff and local communities bordering Ruaha’s protected areas about the links between wildlife, domestic animal, and human health. To achieve this goal we increased on‐the‐ground capacity of Ruaha’s protected areas staff (ecologists, managers, rangers and game scouts) to safely investigate and mitigate zoonotic diseases that pose a conservation threat; and created awareness in communities bordering Ruaha’s protected areas about zoonotic diseases that can be passed between livestock, wildlife, and people, encouraging prevention practices that reduce disease spillover to people and wildlife. A key output of the project was the development of a handbook for “recognizing, investigating, and reporting diseases of concern for wildlife conservation and human health”, which has become a valuable resource for wildlife professionals in the Central and East Africa region.

USAID Global Livestock Collaborative Research Support Program: Health for Animals and Livelihood Improvement (HALI) Project (2006-2009)

Our founding project, HALI evolved as a partnership between the two veterinary schools at the Sokoine University of Agriculture in Tanzania and the University of California Davis Wildlife Health Center and friends with the Wildlife Conservation Society’s Ruaha Landscape Program. Our initial work aimed to characterize zoonotic disease transmission between humans, animals (including wildlife) and the environment, and investigated the impacts of disease transmission on livelihoods and human health in the Ruaha ecosystem.